BackgroundCalcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response. Inhibits PCSK9-enhanced LDLR degradation, probably reduces PCSK9 protein levels via a translational mechanism but also competes with LDLR for binding with PCSK9.
DescriptionANXA2 Recombinant Monoclonal Antibody [10H9]. Unconjugated. Raised in: HEK293F Cell.
FormulationBuffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
SpecificityHuman
IsotypeRabbit IgG
Uniprot IDP07355
PurificationAffinity Chromatography
ImmunogenA synthesized peptide derived from human ANXA2
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Alternative NamesAnnexin A2 (Annexin II) (Annexin-2) (Calpactin I heavy chain) (Calpactin-1 heavy chain) (Chromobindin-8) (Lipocortin II) (Placental anticoagulant protein IV) (PAP-IV) (Protein I) (p36), ANXA2, ANX2 ANX2L4 CAL1H LPC2D
ApplicationELISA, WB, IHC; Recommended dilution: WB:1:500-1:2000, IHC:1:50-1:200