BackgroundCalcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export. Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis.
DescriptionCALR Polyclonal Antibody, FITC Conjugated. FITC. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, pH 7.4.
SpecificityPig
IsotypeIgG
Uniprot IDP28491
Purification>95%, Protein G purified
ImmunogenRecombinant Pig Calreticulin protein (18-417AA)
StorageShipped at 4°C. Upon receipt, store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesCalreticulin, CRP55, Calregulin, Endoplasmic reticulum resident protein 60, ERp60, HACBP, CALR
ApplicationELISA; Recommended dilution: ELISA 1:100-1:500