BackgroundActs at least in part as component of the WASH core complex whose assembly at the surface of endosomes seems to inhibit WASH nucleation-promoting factor (NPF) activity in recruiting and activating the Arp2/3 complex to induce actin polymerization, and which is involved in regulation of the fission of tubules that serve as transport intermediates during endosome sorting (PubMed:19922875, PubMed:20498093).
DescriptionCCDC53 Polyclonal Antibody, FITC Conjugated. FITC. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300. 50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityHuman
IsotypeIgG
Uniprot IDQ9Y3C0
PurificationProtein G purified
ImmunogenRecombinant Human WASH complex subunit 3 protein (1-194AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesWASH complex subunit CCDC53, CCDC53, AD-016, CGI-116, x0009, Coiled-coil domain-containing protein 53
ApplicationELISA; Recommended dilution: ELISA 1:100-1:500