BackgroundThis protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade.
DescriptionCD55 Recombinant Monoclonal Antibody [1A5]. Unconjugated. Raised in: HEK293F Cell.
FormulationBuffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
SpecificityHuman
IsotypeRabbit IgG
Uniprot IDP08174
PurificationAffinity Chromatography
ImmunogenA synthesized peptide derived from human CD55
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Alternative NamesComplement decay-accelerating factor (CD antigen CD55), CD55, CR DAF
ApplicationELISA, WB, IHC; Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200