BackgroundPotent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase.
DescriptionCD59 Polyclonal Antibody, HRP Conjugated. HRP. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityHuman
IsotypeIgG
Uniprot IDP13987
Purification>95%, Protein G purified
ImmunogenRecombinant Human CD59 glycoprotein (26-102AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative Names1F5 antigen 20 kDa homologous restriction factor MAC-inhibitory protein MEM43 antigen Membrane attack complex inhibition factor Membrane inhibitor of reactive lysis Protectin CD_antigen=CD59 CD59 MIC11, MIN1, MIN2, MIN3, MSK21
ApplicationELISA; Recommended dilution: ELISA 1:500-1:1000