BackgroundChannel-forming tight junction protein that mediates paracellular chloride transport in the kidney. Plays a critical role in the paracellular reabsorption of filtered chloride in the kidney collecting ducts. Claudins play a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
DescriptionCLDN4 Recombinant Monoclonal Antibody [2G12]. Unconjugated. Raised in: HEK293F Cell.
FormulationBuffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
SpecificityHuman
IsotypeRabbit IgG
Uniprot IDO14493
PurificationAffinity-chromatography
ImmunogenA synthesized peptide derived from human CLDN4
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Alternative NamesClaudin-4, Clostridium perfringens enterotoxin receptor, CLDN4, CPER, CPETR1, WBSCR8
ApplicationELISA