BackgroundCatalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol.
DescriptionCOMT Recombinant Monoclonal Antibody [8E1]. Unconjugated. Raised in: HEK293F Cell.
FormulationBuffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
SpecificityHuman
IsotypeRabbit IgG
Uniprot IDP21964
PurificationAffinity Chromatography
ImmunogenA synthesized peptide derived from human COMT
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Alternative NamesCatechol O-methyltransferase (EC 2.1.1.6), COMT
ApplicationELISA, WB, IHC; Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200