BackgroundDefensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 1, an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. This gene maps in close proximity to defensin family member, defensin, alpha 1 and has been implicated in the pathogenesis of cystic fibrosis.
DescriptionDEFB1 Recombinant Monoclonal Antibody [1F5]. Unconjugated. Raised in: HEK293F Cell.
FormulationBuffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
SpecificityHuman
IsotypeRabbit IgG
Uniprot IDP60022
PurificationAffinity Chromatography
ImmunogenA synthesized peptide derived from Human DEFB1
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Alternative NamesBeta-defensin 1 (BD-1) (hBD-1) (Defensin, beta 1), DEFB1, BD1 HBD1
ApplicationELISA, FC; Recommended dilution: FC:1:50-1:200