BackgroundAnchors the extracellular matrix to the cytoskeleton via F-actin. Ligand for dystroglycan. Component of the dystrophin-associated glycoprotein complex which accumulates at the neuromuscular junction (NMJ) and at a variety of synapses in the peripheral and central nervous systems and has a structural function in stabilizing the sarcolemma. Also implicated in signaling events and synaptic transmission.
DescriptionDMD Recombinant Monoclonal Antibody [4B10]. Unconjugated. Raised in: HEK293F Cell.
FormulationBuffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
SpecificityHuman
IsotypeRabbit IgG
Uniprot IDP11532
PurificationAffinity Chromatography
ImmunogenA synthesized peptide derived from human Dystrophin
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Alternative NamesDystrophin, DMD
ApplicationELISA, IHC; Recommended dilution: IHC:1:50-1:200