BackgroundMicrotubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Plays a role in the regulation of neuron morphology, axon growth and formation of neuronal growth cones (By similarity). Plays an important role in vesicular trafficking processes, in particular endocytosis. Involved in cytokinesis. Regulates maturation of apoptotic cell corpse-containing phagosomes by recruiting PIK3C3 to the phagosome membrane (By similarity).
DescriptionDNM2 Recombinant Monoclonal Antibody [1D8]. Unconjugated. Raised in: HEK293F Cell.
FormulationBuffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
SpecificityHuman, Rat
IsotypeRabbit IgG
Uniprot IDP50570
PurificationAffinity Chromatography
ImmunogenA synthesized peptide derived from human Dynamin 2
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Alternative NamesDynamin-2 (EC 3.6.5.5), DNM2, DYN2
ApplicationELISA, WB, IF, FC; Recommended dilution: WB:1:500-1:5000, IF:1:20-1:200, FC:1:20-1:200