BackgroundCatalyzes the first and rate-limiting reaction of the four that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. May participate to the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
DescriptionELOVL5 Polyclonal Antibody, Biotin Conjugated. Biotin. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityHuman
IsotypeIgG
Uniprot IDQ9NYP7
Purification>95%, Protein G purified
ImmunogenRecombinant Human Elongation of very long chain fatty acids protein 5 protein (247-299AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesElongation of very long chain fatty acids protein 5, 3-keto acyl-CoA synthase ELOVL5, ELOVL fatty acid elongase 5, ELOVL FA elongase 5, Fatty acid elongase 1, hELO1, Very-long-chain 3-oxoacyl-CoA synthase 5, ELOVL5, ELOVL2, PRO0530
ApplicationELISA; Recommended dilution: ELISA 1:500-1:1000