BackgroundThrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing.
DescriptionF2 Recombinant Monoclonal Antibody [9A1]. Unconjugated. Raised in: HEK293F Cell.
FormulationBuffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
SpecificityHuman
IsotypeRabbit IgG
Uniprot IDP00734
PurificationAffinity-chromatography
ImmunogenA synthesized peptide derived from human Prothrombin
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Alternative NamesProthrombin (EC 3.4.21.5) (Coagulation factor II) [Cleaved into: Activation peptide fragment 1, Activation peptide fragment 2, Thrombin light chain, Thrombin heavy chain], F2
ApplicationELISA, IHC; Recommended dilution: IHC:1:50-1:200