BackgroundConverts glutamate to gamma-aminobutyrate (GABA), consuming one intracellular proton in the reaction. The gad system helps to maintain a near-neutral intracellular pH when cells are exposed to extremely acidic conditions. The ability to survive transit through the acidic conditions of the stomach is essential for successful colonization of the mammalian host by commensal and pathogenic bacteria.
DescriptiongadA Polyclonal Antibody, Biotin Conjugated. Biotin. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityEscherichia coli
IsotypeIgG
Uniprot IDP69908
Purification>95%, Protein G purified
ImmunogenRecombinant Escherichia coli Glutamate decarboxylase alpha protein (1-466AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesgadA , gadS , b3517, JW3485
ApplicationELISA; Recommended dilution: ELISA 1:500-1:1000