BackgroundGCN5L2, also known as KAT2A or GCN5, is a component of the ATAC complex and promotes transcription activation by acting as a histone acetyltransferase (HAT). GSN5L2 is known to have significant histone acetyltransferase activity among core histones, but no histone acetyltransferase activity with core particles of the nucleosome. The ATAC complex which it is a part of is specifically involved in histone H3 and H4 acetyltransferase activity.
DescriptionMouse monoclonal antibody raised against a partial recombinant GCN5L2, clone 4D3.
Size100 µg
PurificationProtein A purified
ImmunogenGCN5L2 (AAH32743, 738 a.a. ~ 838 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Cross ReactivityHuman
IsotypeIgG2b Kappa
FormulationIn 1x PBS, pH 7.2
StorageAliquot and store at -20ºC or lower. Avoid repeated freezing and thawing. Multiple freeze/thaw cycles may result in decreased performance.
Handling RecommendationsFor maximum recovery of the products, centrifuge the vial prior to opening the cap.
Alternative Names1110051E14Rik antibody, AW212720 antibody, EC 2.3.1.48 antibody, GCN 5 antibody, GCN5 like 2 antibody, GCNL 2 antibody, General control of amino acid synthesis protein 5 like 2 antibody, HGCN 5 antibody, Histone acetyltransferase GCN5 antibody, Histone acetyltransferase KAT2A antibody, hsGCN5 antibody, K (lysine) acetyltransferase 2A antibody, KAT 2A antibody, MGC102791 antibody, PCAF b antibody, STAF 97 antibody
Applications & Suggested Dilutions*Western Blot: 0.5-1 µg/mlELISA: 0.25-1 µg/mlImmunofluorescence: 5 µg/ml
*The end user is responsible for determining optimal working dilutions.
Quality ControlWestern Blot detection against Immunogen (37.11 KDa).
Note: This item was formerly catalog no. ABB-4056 (ABB4056)
Applications
Western Blot
GCN5L2 Monoclonal Antibody [4D3]. Western Blot analysis of GCN5L2 expression in K-562.
ELISA
Immunohistochemistry (IHC)