BackgroundMaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit, which is the product of this gene, and the modulatory beta subunit. Intracellular calcium regulates the physical association between the alpha and beta subunits. Alternatively spliced transcript variants encoding different isoforms have been identified.
DescriptionKCNMA1 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
FormulationBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
SpecificityRat
IsotypeIgG
Uniprot IDQ12791
PurificationAffinity Purification
ImmunogenA synthetic peptide corresponding to a sequence within amino acids 850-950 of human KCNMA1 (NP_001258447.1).
StorageShipped at 4°C. Upon receipt, store at -20°C. Avoid freeze / thaw cycles
Alternative NamesKCNMA1; BKTM; KCa1.1; MaxiK; SAKCA; SLO; SLO-ALPHA; SLO1; bA205K10.1; hSlo; mSLO1; calcium-activated potassium channel subunit alpha-1
ApplicationWB; Recommended dilution: WB 1:200 - 1:2000