BackgroundAttaches the virion to the host cell membrane by interacting with heparan sulfate, initiating the infection. Interacts with host CX3CR1, the receptor for the CX3C chemokine fractalkine, to modulate the immune response and facilitate infection. Unlike the other paramyxovirus attachment proteins, lacks both neuraminidase and hemagglutinating activities. Secreted glycoprotein G helps RSV escape antibody-dependent restriction of replication by acting as an antigen decoy and by modulating the activity of leukocytes bearing Fcgamma receptors.
DescriptionMajor Surface Glycoprotein G Polyclonal Antibody, FITC Conjugated. FITC. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityHuman respiratory syncytial virus A
IsotypeIgG
Uniprot IDP03423
Purification>95%, Protein G purified
ImmunogenRecombinant Human respiratory syncytial virus A Major surface glycoprotein G protein (67-298AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesAttachment glycoprotein G, Membrane-bound glycoprotein, mG, G
ApplicationELISA; Recommended dilution: ELISA 1:100-1:500