BackgroundThis gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP).
DescriptionMERTK Recombinant Monoclonal Antibody [8H11]. Unconjugated. Raised in: HEK293F Cell.
FormulationBuffer: 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityHuman
IsotypehIgG4 (S228P)
Uniprot IDQ12866
PurificationAffinity Chromatography
ImmunogenRecombinant Human MERTK protein
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Alternative NamesTyrosine-protein kinase Mer (EC 2.7.10.1) (Proto-oncogene c-Mer) (Receptor tyrosine kinase MerTK), MERTK, MER
ApplicationELISA