BackgroundRequired for collagen VII (COL7A1) secretion by loading COL7A1 into transport carriers. May participate in cargo loading of COL7A1 at endoplasmic reticulum exit sites by binding to COPII coat subunits Sec23/24 and guiding SH3-bound COL7A1 into a growing carrier. Does not play a role in global protein secretion and is apparently specific to COL7A1 cargo loading. However, it may participate in secretion of other proteins in cells that do not secrete COL7A1.
DescriptionMIA3 Polyclonal Antibody, HRP Conjugated. HRP. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300. 50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityHuman
IsotypeIgG
Uniprot IDQ5JRA6
PurificationProtein G purified
ImmunogenRecombinant Human Transport and Golgi organization protein 1 homolog protein (1447-1626AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesMelanoma inhibitory activity protein 3, C219-reactive peptide, D320, Transport and Golgi organization protein 1, MIA3, KIAA0268, TANGO, TANGO1, UNQ6077/PRO20088
ApplicationELISA; Recommended dilution: ELISA 1:500-1:1000