BackgroundMay activate or repress transcription via interactions with sequence specific DNA-binding proteins. Repression may be mediated at least in part by histone deacetylase activity (HDAC activity). Acts as a corepressor and in concert with CRY1, represses the transcription of the core circadian clock component PER2. Preferentially binds to dimethylated histone H3 'Lys-9' (H3K9me2) on the PER2 promoter.
DescriptionMYBBP1A Recombinant Monoclonal Antibody [3A1]. Unconjugated. Raised in: HEK293F Cell.
FormulationBuffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
SpecificityHuman
IsotypeRabbit IgG
Uniprot IDQ9BQG0
PurificationAffinity Chromatography
ImmunogenA synthesized peptide derived from human MYBBP1A
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Alternative NamesMyb-binding protein 1A, MYBBP1A, P160
ApplicationELISA, IHC, IF; Recommended dilution: IHC:1:50-1:200, IF:1:20-1:200