BackgroundThis gene is a member of the myosin gene family. Myosins are mechanochemical proteins characterized by the presence of a motor domain, an actin-binding domain, a neck domain that interacts with other proteins, and a tail domain that serves as an anchor. This gene encodes an unconventional myosin with a very short tail. Defects in this gene are associated with the mouse shaker-1 phenotype and the human Usher syndrome 1B which are characterized by deafness, reduced vestibular function, and (in human) retinal degeneration. Alternative splicing results in multiple transcript variants.
DescriptionMYO7A Recombinant Monoclonal Antibody [31A12]. Unconjugated. Raised in: HEK293F Cell.
FormulationBuffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
SpecificityHuman
IsotypeRabbit IgG
Uniprot IDQ13402
PurificationAffinity Chromatography
ImmunogenA synthesized peptide derived from Human MYO7A
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Alternative NamesUnconventional myosin-VIIa, MYO7A, USH1B
ApplicationELISA, FC; Recommended dilution: FC:1:50-1:200