BackgroundActs as guanine nucleotide exchange factor (GEF) for RhoA GTPase. May be involved in activation of the SAPK/JNK pathway Stimulates genotoxic stress-induced RHOB activity in breast cancer cells leading to their cell death.
DescriptionNET1 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityHuman
IsotypeIgG
Uniprot IDQ7Z628
Purification>95%, Protein G purified
ImmunogenRecombinant Human Neuroepithelial cell-transforming gene 1 protein (1-542AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesProto-oncogene p65 Net1, Rho guanine nucleotide exchange factor 8, NET1, ARHGEF8
ApplicationELISA