BackgroundActs as a transcriptional activator. Required for the maintenance of NEUROD1 expression in the horomone-producing endocrine cells of the pancreas. May be involved in specifying diencephalic neuromeric boundaries, and in controlling the expression of genes that play a role in axonal guidance. Associates with chromatin at the NEUROD1 promoter region. Binds to a subset of consensus elements within the NEUROD1 promoter.
DescriptionNkx2-2 Polyclonal Antibody, Biotin Conjugated. Biotin. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityMouse
IsotypeIgG
Uniprot IDP42586
Purification>95%, Protein G purified
ImmunogenRecombinant Mouse Homeobox protein Nkx-2.2 protein (1-273AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesHomeobox protein Nkx-2.2, Nkx2-2, Nkx-2.2, Nkx2b, Homeobox protein NK-2 homolog B
ApplicationELISA; Recommended dilution: ELISA 1:500-1:1000