BackgroundActs as a transcriptional regulator. Acts as a negative regulator of receptor-dependent signaling pathways. Specifically inhibits transactivation of the nuclear receptor with whom it interacts. Inhibits transcriptional activity of NEUROD1 on E-box-containing promoter by interfering with the coactivation function of the p300/CBP-mediated trancription complex for NEUROD1.
DescriptionNR0B2 Polyclonal Antibody, FITC Conjugated. FITC. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityHuman
IsotypeIgG
Uniprot IDQ15466
Purification>95%, Protein G purified
ImmunogenRecombinant Human Nuclear receptor subfamily 0 group B member 2 protein (1-257AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesNuclear receptor subfamily 0 group B member 2, NR0B2, SHP, Orphan nuclear receptor SHP, Small heterodimer partner
ApplicationELISA; Recommended dilution: ELISA 1:100-1:500