BackgroundFlavoenzyme which catalyzes the oxidation of N(1)-acetylspermine to spermidine and is thus involved in the polyamine back-conversion. Can also oxidize N(1)-acetylspermidine to putrescine. Substrate specificity: N(1)-acetylspermine = N(1)-acetylspermidine > N(1),N(12)-diacylspermine >> spermine. Does not oxidize spermidine. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs.
DescriptionPaox Polyclonal Antibody, HRP Conjugated. HRP. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300. 50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityMouse
IsotypeIgG
Uniprot IDQ8C0L6
PurificationProtein G purified
ImmunogenRecombinant Mouse Peroxisomal N(1)-acetyl-spermine/spermidine oxidase protein (1-504AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesPeroxisomal N(1)-acetyl-spermine/spermidine oxidase, Polyamine oxidase, Paox, Pao
ApplicationELISA; Recommended dilution: ELISA 1:500-1:1000