BackgroundThis gene encodes a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. Alternatively spliced transcript variants encoding different isoforms have been described.
DescriptionPAX8 Recombinant Monoclonal Antibody [17F10]. Unconjugated. Raised in: HEK293F Cell.
FormulationBuffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
SpecificityHuman
IsotypeRabbit IgG
Uniprot IDQ06710
PurificationAffinity Chromatography
ImmunogenA synthesized peptide derived from Human PAX8
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Alternative NamesPaired box protein Pax-8, PAX8
ApplicationELISA, IHC; Recommended dilution: IHC:1:50-1:200