BackgroundPlays an essential role in pregnancy establishment by proteolytic activation of a number of important factors such as BMP2, CALD1 and alpha-integrins. Likely to represent a widespread endoprotease activity within the constitutive and regulated secretory pathway. Capable of cleavage at the RX(K/R)R consensus motif. May be responsible for the maturation of gastrointestinal peptides. May be involved in the cellular proliferation of adrenal cortex via the activation of growth factors.
DescriptionPcsk5 Polyclonal Antibody, Biotin Conjugated. Biotin. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityMouse
IsotypeIgG
Uniprot IDQ04592
Purification>95%, Protein G purified
ImmunogenRecombinant Mouse Proprotein convertase subtilisin/kexin type 5 protein (117-452AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesProprotein convertase subtilisin/kexin type 5, Proprotein convertase 5, PC5, Proprotein convertase 6, PC6, Subtilisin-like proprotein convertase 6, SPC6, Subtilisin/kexin-like protease PC5, Pcsk5
ApplicationELISA; Recommended dilution: ELISA 1:500-1:1000