BackgroundLikely to represent a widespread endoprotease activity within the constitutive and regulated secretory pathway. Capable of cleavage at the RX(K/R)R consensus motif. Plays an essential role in pregnancy establishment by proteolytic activation of a number of important factors such as BMP2, CALD1 and alpha-integrins.
DescriptionPCSK5 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
Formulation0.03% Proclin 300. 50% Glycerol, 0.01M PBS, pH 7.4.
SpecificityHuman, Rat
IsotypeIgG
Uniprot IDQ92824
PurificationProtein G purified
ImmunogenRecombinant Human Proprotein convertase subtilisin/kexin type 5 protein (201-500AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesProprotein convertase subtilisin/kexin type 5, Proprotein convertase 5, PC5, Proprotein convertase 6, PC6, hPC6, Subtilisin/kexin-like protease PC5, PCSK5, PC5, PC6
ApplicationELISA, WB, IHC, IF; Recommended dilution: WB:1:500-5000, IHC:1:200-1:500, IF:1:50-1:200