BackgroundPrevents apoptosis in hepatocellular carcinoma (HCC) cells through interaction with SIAH1, a mediator of apoptosis. May also have a role in cell growth promotion and hepatoma formation. Inhibits the TGF-beta signaling by interacting with the TGF-beta receptor ALK1. When overexpressed, induces the formation of cellular extension, such as filipodia in association with ALK1. Involved at the immediate early stage of adipocyte differentiation By similarity. May bind to the 5'-GCCTGTCTTT-3' DNA sequence of the MB1 domain in the myelin basic protein (MBP) promoter
DescriptionPEG10 Polyclonal Antibody, HRP Conjugated. HRP. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityHuman
IsotypeIgG
Uniprot IDQ86TG7
Purification>95%, Protein G purified
ImmunogenRecombinant Human Retrotransposon-derived protein PEG10 protein (1-325AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesEmbryonal carcinoma differentiation-regulated protein Mammalian retrotransposon-derived protein 2 Myelin expression factor 3-like protein 1 Paternally expressed gene 10 protein Retrotransposon gag domain-containing protein 3 Retrotransposon-derived gag-like polyprotein Ty3/Gypsy-like protein PEG10 EDR, KIAA1051, MAR2, MART2, MEF3L1, RGAG3
ApplicationELISA; Recommended dilution: ELISA 1:500-1:1000