BackgroundPHGDH or 3-phosphoglycerate dehydrogenase is an enzyme belonging to the D-isomer specific 2-hydroxyacid dehydrogenase family. It catalysis the reaction 3-phosphoglycerate + NAD+ = 3-phosphonooxypyruvate + NADH during L-serine biosynthesis. Defects in PHGDH are the cause of phosphoglycerate dehydrogenase deficiency (PHGDH deficiency). It is characterized by congenital microcephaly, psychomotor retardation and seizures.
DescriptionPHGDH Polyclonal Antibody, FITC Conjugated. FITC. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityHuman
IsotypeIgG
Uniprot IDO43175
Purification>95%, Protein G purified
ImmunogenRecombinant Human D-3-phosphoglycerate dehydrogenase protein (2-251AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative Names3-PGDH