BackgroundThis gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
DescriptionPhospho-RPS6KA1 (T359/S363) Recombinant Monoclonal Antibody [1B6]. Unconjugated. Raised in: HEK293F Cell.
FormulationBuffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
SpecificityHuman
IsotypeRabbit IgG
Uniprot IDQ15418
PurificationAffinity Chromatography
ImmunogenA synthesized peptide derived from human Phospho-RPS6KA1 (T359+S363)
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Alternative NamesRibosomal protein S6 kinase alpha-1, S6K-alpha-1, 90 kDa ribosomal protein S6 kinase 1, p90-RSK 1, p90RSK1, p90S6K, MAP kinase-activated protein kinase 1a, MAPK-activated protein kinase 1a, MAPKAP kinase 1a, MAPKAPK-1a, Ribosomal S6 kinase 1, RSK-1, RPS6KA1, MAPKAPK1A, RSK1
ApplicationELISA, WB, IF, IP; Recommended dilution: WB:1:500-1:5000, IF:1:20-1:200, IP:1:200-1:1000