BackgroundPI3K phosphorylates PtdIns lipids to generate PIP3, recruiting proteins for cell growth, survival, and signaling. Activated by GPCR and tyrosine kinases, crucial for platelet function and adhesion. Influences autophagy, insulin signaling, and cell migration. Key in oncogenic transformation and tumor growth.
DescriptionPIK3CB Recombinant Monoclonal Antibody [5A9]. Unconjugated. Raised in: HEK293F Cell.
FormulationBuffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
SpecificityHuman
IsotypeRabbit IgG
Uniprot IDP42338
PurificationAffinity Chromatography
ImmunogenA synthesized peptide derived from human PI3 Kinase p110 beta
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Alternative NamesPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (PI3-kinase subunit beta) (PI3K-beta) (PI3Kbeta) (PtdIns-3-kinase subunit beta) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit beta) (PtdIns-3-kinase subunit p110-beta) (p110beta), PIK3CB, PIK3C1
ApplicationELISA, WB, IP; Recommended dilution: WB:1:500-1:5000, IP:1:200-1:1000