BackgroundHydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. Capable of hydrolyzing a broad spectrum of organophosphate substrates and lactones, and a number of aromatic carboxylic acid esters. Mediates an enzymatic protection of low density lipoproteins against oxidative modification and the consequent series of events leading to atheroma formation.
DescriptionPON1 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityHuman, Mouse
IsotypeIgG
Uniprot IDP27169
Purification>95%, Protein G purified
ImmunogenRecombinant Human Serum paraoxonase/arylesterase 1 protein (2-355AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesAromatic esterase 1, K-45, Serum aryldialkylphosphatase 1, PON1, PON
ApplicationELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200