BackgroundInvolved in the regulation of cell survival. Promotes invasive migration of cells in which it functions to localize and maintain integrin alpha-V/beta-1 at the tips of extending pseudopodia. Involved in the regulation of epithelial morphogenesis through the control of CLDN4 expression and localization at tight junctions (By similarity). May selectively regulate the apical recycling pathway. Together with MYO5B regulates transcytosis (By similarity).
DescriptionRAB25 Recombinant Monoclonal Antibody [27H3]. Unconjugated. Raised in: HEK293F Cell.
FormulationBuffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
SpecificityHuman
IsotypeRabbit IgG
Uniprot IDP57735
PurificationAffinity Chromatography
ImmunogenA synthesized peptide derived from human RAB25
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Alternative NamesRas-related protein Rab-25 (CATX-8), RAB25, CATX8
ApplicationELISA, IF; Recommended dilution: IF:1:50-1:200