BackgroundPlasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as secretory processes, phagocytose of apoptotic cells and epithelial cell polarization. Augments the production of reactive oxygen species (ROS) by NADPH oxidase.
DescriptionRAC2 Polyclonal Antibody, Biotin Conjugated. Biotin. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityHuman
IsotypeIgG
Uniprot IDP15153
Purification>95%, Protein G purified
ImmunogenRecombinant Human Ras-related C3 botulinum toxin substrate 2 protein (1-189AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesRas-related C3 botulinum toxin substrate 2, GX, Small G protein, p21-Rac2, RAC2
ApplicationELISA; Recommended dilution: ELISA 1:500-1:1000