BackgroundInvolved in the first step of pre-mRNA splicing. Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic phases of the spliceosome cycle. Involved in both translocations of the nuclear SLU7 to the cytoplasm and the cytosolic calcium-binding protein PDCD6 to the nucleus upon cellular stress responses.
DescriptionRBM22 Polyclonal Antibody, FITC Conjugated. FITC. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityHuman
IsotypeIgG
Uniprot IDQ9NW64
Purification>95%, Protein G purified
ImmunogenRecombinant Human Pre-mRNA-splicing factor RBM22 protein (2-250AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesPre-mRNA-splicing factor RBM22, RNA-binding motif protein 22, Zinc finger CCCH domain-containing protein 16, RBM22, ZC3H16, 199G4
ApplicationELISA; Recommended dilution: ELISA 1:100-1:500