BackgroundThe RIC1-RGP1 complex acts as a guanine nucleotide exchange factor (GEF), which activates RAB6A by exchanging bound GDP for free GTP and may thereby required for efficient fusion of endosome-derived vesicles with the Golgi compartment. The RIC1-RGP1 complex participates in the recycling of mannose-6-phosphate receptors.
DescriptionRGP1 Polyclonal Antibody, HRP Conjugated. HRP. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityHuman
IsotypeIgG
Uniprot IDQ92546
Purification>95%, Protein G purified
ImmunogenRecombinant Human RAB6A-GEF complex partner protein 2 protein (56-350AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesRAB6A-GEF complex partner protein 2Curated, RGP1, Retrograde Golgi transport protein RGP1 homolog
ApplicationELISA; Recommended dilution: ELISA 1:500-1:1000