BackgroundActivates the protein kinase activity of mTORC1, and thereby plays a role in the regulation of apoptosis. Stimulates the phosphorylation of S6K1 and EIF4EBP1 through activation of mTORC1 signaling. Has low intrinsic GTPase activity.
DescriptionRHEB Recombinant Monoclonal Antibody [7G7]. Unconjugated. Raised in: HEK293F Cell.
FormulationBuffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
SpecificityHuman
IsotypeRabbit IgG
Uniprot IDQ15382
PurificationAffinity Chromatography
ImmunogenA synthesized peptide derived from human RHEB
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Alternative NamesGTP-binding protein Rheb (Ras homolog enriched in brain), RHEB, RHEB2
ApplicationELISA, IF; Recommended dilution: IF:1:20-1:200