BackgroundThis gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants have been identified.
DescriptionRhoA Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
FormulationBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
SpecificityHuman, Mouse, Rat
IsotypeIgG
Uniprot IDP61586
PurificationAffinity Purification
ImmunogenA synthetic peptide corresponding to a sequence within amino acids 100 to the C-terminus of human RhoA (NP_001655.1).
StorageShipped at 4°C. Upon receipt, store at -20°C. Avoid freeze / thaw cycles
Alternative NamesRHOA; ARH12; ARHA; RHO12; RHOH12; transforming protein RhoA
ApplicationWB, IHC, IF