BackgroundEssential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. Promotes TOP3A binding to double Holliday junctions (DHJ) and hence stimulates TOP3A-mediated dissolution. Required for BLM phosphorylation during mitosis. Within the BLM complex, required for BLM and TOP3A stability.
DescriptionRMI1 Polyclonal Antibody, Biotin Conjugated. Biotin. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityHuman
IsotypeIgG
Uniprot IDQ9H9A7
Purification>95%, Protein G purified
ImmunogenRecombinant Human RecQ-mediated genome instability protein 1 protein (181-443AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesRecQ-mediated genome instability protein 1, BLM-associated protein of 75 kDa, BLAP75, FAAP75, RMI1, C9orf76
ApplicationELISA; Recommended dilution: ELISA 1:500-1:1000