BackgroundE3 ubiquitin-protein ligase involved in angiogenesis. Involved in the non-canonical Wnt signaling pathway in vascular development: acts by mediating ubiquitination and degradation of FLNA and NFATC2 downstream of RSPO3, leading to inhibit the non-canonical Wnt signaling pathway and promoting vessel regression. Also has ATPase activity.
DescriptionRNF213 Polyclonal Antibody, FITC Conjugated. FITC. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, pH 7.4.
SpecificityHuman
IsotypeIgG
Uniprot IDQ63HN8
Purification>95%, Protein G purified
ImmunogenRecombinant Human E3 ubiquitin-protein ligase RNF213 protein (202-350AA)
StorageShipped at 4°C. Upon receipt, store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesE3 ubiquitin-protein ligase RNF213, ALK lymphoma oligomerization partner on chromosome 171, RNF213
ApplicationELISA; Recommended dilution: ELISA 1:100-1:500