BackgroundThis gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains a kinase catalytic domain and phosphorylates the S6 ribosomal protein and eukaryotic translation initiation factor 4B (eIF4B). Phosphorylation of S6 leads to an increase in protein synthesis and cell proliferation.
DescriptionRPS6KB2 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
FormulationBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
SpecificityHuman, Mouse, Rat
IsotypeIgG
Uniprot IDQ9UBS0
PurificationAffinity Purification
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 1-170 of human RPS6KB2 (NP_003943.2).
StorageShipped at 4°C. Upon receipt, store at -20°C. Avoid freeze / thaw cycles
Alternative NamesRPS6KB2; KLS; P70-beta; P70-beta-1; P70-beta-2; S6K-beta2; S6K2; SRK; STK14B; p70(S6K)-beta; p70S6Kb; ribosomal protein S6 kinase B2
ApplicationWB, IHC; Recommended dilution: WB 1:500 - 1:1000, IHC 1:50 - 1:100