BackgroundPutative signaling adapter which may play a role in neuronal differentiation. May be involved in regulation of NGF-dependent neurite outgrowth. Proposed to play a role in neuronal vesicular trafficking, specifically involving pre-synaptic membrane proteins. Seems to be involved in signaling pathways that are regulated by the prolonged activation of MAPK. Can regulate the polyubiquitination of IKBKG and thus may be involved in regulation of the NF-kappa-B pathway.
DescriptionRUSC1 Polyclonal Antibody, HRP Conjugated. HRP. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityHuman
IsotypeIgG
Uniprot IDQ9BVN2
Purification>95%, Protein G purified
ImmunogenRecombinant Human RUN and SH3 domain-containing protein 1 protein (231-433AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesRUN and SH3 domain-containing protein 1, RUSC1, NESCA, New molecule containing SH3 at the carboxy-terminus, Nesca
ApplicationELISA; Recommended dilution: ELISA 1:500-1:1000