BackgroundHost restriction nuclease that blocks early-stage virus replication in dendritic and other myeloid cells. May function by reducing the cellular dNTP levels to levels too low for retroviral reverse transcription to occur. May play a role in mediating proinflammatory responses to TNF-alpha signaling.
DescriptionSAMHD1 Polyclonal Antibody, Biotin Conjugated. Biotin. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300. 50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityMouse
IsotypeIgG
Uniprot IDQ9Y3Z3
PurificationProtein G purified
ImmunogenRecombinant Mouse Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 protein (426-657AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesDendritic cell-derived IFNG-induced protein, Monocyte protein 5, SAM domain and HD domain-containing protein 1, SAMHD1, MOP5
ApplicationELISA