BackgroundThe protein encoded by this gene is a coiled-coil-forming protein that associates with the SNARE (soluble N-ethylmaleimide-sensitive fusion protein attachment protein receptor) complex of proteins and the BLOC-1 (biogenesis of lysosome-related organelles) complex. Biochemical studies have identified additional binding partners. As part of the SNARE complex, it is required for vesicle docking and fusion and regulates neurotransmitter release. The BLOC-1 complex is required for the biogenesis of specialized organelles such as melanosomes and platelet dense granules. Mutations in gene products that form the BLOC-1 complex have been identified in mouse strains that are models of Hermansky-Pudlak syndrome. Alternative splicing results in multiple transcript variants.
DescriptionSNAPIN Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
FormulationBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
SpecificityHuman, Mouse, Rat
IsotypeIgG
Uniprot IDO95295
PurificationAffinity Purified
ImmunogenRecombinant protein of human SNAPIN.
StorageShipped at 4°C. Store at -20°C. Avoid freeze / thaw cycles.
Alternative NamesSNAPIN; BLOC1S7; BLOS7; BORCS3; SNAPAP
ApplicationWB; Recommended dilution: WB 1:200 - 1:2000