BackgroundPlasma membrane t-SNARE that mediates docking of transport vesicles. Necessary for the translocation of SLC2A4 from intracellular vesicles to the plasma membrane. Together with STXB3 and VAMP2, may also play a role in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes (By similarity). May also play a role in docking of synaptic vesicles at presynaptic active zones.
DescriptionSTX4 Recombinant Monoclonal Antibody [4E1]. Unconjugated. Raised in: HEK293F Cell.
FormulationBuffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
SpecificityHuman
IsotypeRabbit IgG
Uniprot IDQ12846
PurificationAffinity Chromatography
ImmunogenA synthesized peptide derived from human Syntaxin 4
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Alternative NamesSyntaxin-4 (Renal carcinoma antigen NY-REN-31), STX4, STX4A
ApplicationELISA, WB; Recommended dilution: WB:1:500-1:5000