BackgroundThe protein encoded by this gene localizes to the primary cilium and to the plasma membrane. The gene functions in centriole migration to the apical membrane and formation of the primary cilium. Multiple transcript variants encoding different isoforms have been found for this gene. Defects in this gene are a cause of Meckel syndrome type 3 (MKS3) and Joubert syndrome type 6 (JBTS6).
DescriptionTMEM67 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
FormulationBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
SpecificityMouse, Rat
IsotypeIgG
Uniprot IDQ5HYA8
PurificationAffinity Purification
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 780-940 of human TMEM67 (NP_714915.3).
StorageShipped at 4°C. Upon receipt, store at -20°C. Avoid freeze / thaw cycles
Alternative NamesTMEM67; JBTS6; MECKELIN; MKS3; NPHP11; TNEM67; meckelin
ApplicationWB; Recommended dilution: WB 1:200 - 1:2000