BackgroundPolyglutamylase which preferentially modifies alpha-tubulin. Involved in the side-chain initiation step of the polyglutamylation reaction rather than in the elongation step. Required for CCSAP localization to both spindle and cilia microtubules. Increases the effects of NCOA2 in glucocorticoid receptor-mediated repression and induction and in androgen receptor-mediated induction (PubMed:17116691, PubMed:22493317).
DescriptionTTLL5 Polyclonal Antibody, HRP Conjugated. HRP. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityHuman
IsotypeIgG
Uniprot IDQ6EMB2
Purification>95%, Protein G purified
ImmunogenRecombinant Human Tubulin polyglutamylase TTLL5 protein (1-269AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesTubulin polyglutamylase TTLL5 (EC:6.-.-.-), TTLL5, KIAA0998, STAMP, SRC1 and TIF2-associated modulatory protein, Tubulin--tyrosine ligase-like protein 5
ApplicationELISA; Recommended dilution: ELISA 1:500-1:1000