BackgroundThis gene encodes a protein belonging to the 14-3-3 family of proteins, members of which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals. The encoded protein has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery. Two transcript variants, which encode the same protein, have been identified for this gene.
DescriptionYWHAB Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
FormulationBuffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3.
SpecificityHuman, Mouse
IsotypeIgG
Uniprot IDP31946
PurificationAffinity Purification
ImmunogenA synthetic peptide corresponding to a sequence within amino acids 150-246 of human 14-3-3 alpha/beta (NP_003395.1).
StorageShipped at 4°C. Upon receipt, store at -20°C. Avoid freeze / thaw cycles
Alternative NamesYWHAB; GW128; HEL-S-1; HS1; KCIP-1; YWHAA; 14-3-3 protein beta/alpha
ApplicationWB, IHC, IF, IP; Recommended dilution: ELISA, WB, IHC, IF, IP; Recommended dilution: WB: 1:500-1:2000, IHC: 1:50-1:100, IF:1:50-1:200, IP: 0.5μg-4μg antibody for 200μg-400μg extracts of whole cells